Synthesis of carbohydrate-templated amino acids and methods of using same
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United States of America Patent
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May 31, 2011
Grant Date -
Nov 6, 2008
app pub date -
Sep 18, 2007
filing date -
Sep 18, 2006
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Abstract
The present invention generally relates to tetrahydropyranyl-derivatized amino acids, their syntheses and their incorporation into peptides and peptidomimetics. The tetrahydropyran moiety constrains the side chain of an amino acid, thereby providing a molecule that may act as a sugar- or amino acid-mimetic as well as a scaffold for combinatorial synthesis.
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