Prolonged Transit Time of Permeability-Enhancing Drug Eluting Pill
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United States of America Patent
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N/A
Issued Date -
Nov 6, 2008
app pub date -
Dec 14, 2005
filing date -
Dec 14, 2004
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Apparatus is provided for drug administration. The apparatus includes an ingestible capsule, which includes a drug, stored by the capsule. The apparatus also includes an environmentally-sensitive mechanism, adapted to change a state thereof responsively to a disposition of the capsule within a gastrointestinal (GI) tract of a subject; one or more drug-passage facilitation electrodes; and a control component, adapted to facilitate passage of the drug, in response to a change of state of the environmentally-sensitive mechanism, by driving the drug-passage facilitation electrodes to apply an electrical current. The apparatus further includes a velocity-reduction element adapted to reduce a velocity of the capsule through the GI tract for at least a portion of the time that the control component is facilitating the passage of the drug. Additional embodiments are also described.
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