Inhibition of Bradykinin Release
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United States of America Patent
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Issued Date -
Nov 13, 2008
app pub date -
Nov 15, 2007
filing date -
Apr 29, 1999
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The invention is related to a method for treating or preventing a disorder resulting from the release of bradykinin in said mammal, particularly a mammal which produces a HBP which binds to a HBP antagonist, e.g. a monoclonal antibody that binds to at least one epitope of human HBP, comprising administering to said mammal a HBP antagonist in an amount effective to decrease the release of bradykinin in a mammal. Furthermore, the invention is directed to methods and kits for determining if a mammal produces HBP that binds to a HBP antagonist, e.g., a monoclonal antibody that binds to at least one epitope of human HBP and a method for detecting an antagonist of HBP.
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