Importance

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Abstract

A compound represented by formula (I'): (wherein m, n, and p each represent 0 to 2; q represents 0 or 1; R.sup.1 represents halogen, a hydrocarbon group, a heterocyclic group, an alkoxy group, an alkoxycarbonyl group, a sulfamoyl group, a CN group, an NO.sub.2 group, or the like; R.sup.2 represents halogen, amino, a hydrocarbon group, an aromatic heterocyclic group, or an oxo group; X.sub.1 represents O, --NR.sup.3--, or --S(O)r-; X.sub.2 represents a methylene group, O, --NR.sup.3--, or --S(O)r-; Q' represents a heteroaryl group, a heteroarylalkyl group, a substituted aryl group, or an aralkyl group; Cycle moiety represents an aryl ring or a heteroaryl ring; and the wavy line represents an E-isomer or a Z-isomer), a salt of the compound, or a solvate of the compound or the salt. A pharmaceutical composition and a transient receptor potential type I (TRPV1) receptor antagonist each contain, as an active ingredient, at least one of the compound, a salt of the compound, and a solvate of the compound or the salt.

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First Claim