Assays for diagnosis and therapeutics employing similarities and differences in blood serum concentrations of 3 forms of complement C3c and related protein biomarkers between amyotrophic lateral sclerosis and Parkinson's disease

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United States of America Patent

APP PUB NO 20080289964A1
SERIAL NO

11507337

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Abstract

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The invention relates to assays for diagnosis, drug targeting and therapeutic response monitoring, of patients with Parkinson's disease (PD), with PD-Like disorders that express symptoms like PD, age-matched controls (Normal), Patients with Amyotrophic Lateral Sclerosis (ALS), with ALS-Like disorders that express symptoms like ALS, and age-matched controls (Normal). The method is based on the use of 2-dimensional (2D) gel electrophoresis to separate the complex mixture of proteins found in blood serum, the quantitation of a group of identified biomarkers, and the biostatistical analysis of the concentration of the identified biomarkers.

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Patent OwnerAddress
NEOGENOMICS INC AKA NEOGENOMICS LABORATORIES12701 COMMONWEALTH DRIVE SUITE 5 FORT MEYERS FL 33913

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Appel, Stanley H Houston, TX 15 201
Goldknopf, Ira Leonard The Woodlands, TX 10 40
Sheta, Essam Ahmed The Woodlands, EG 7 37

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