Methods and Compositions for Ultra-High Throughput Screening of Natural Products
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United States of America Patent
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Issued Date -
Dec 25, 2008
app pub date -
Dec 16, 2005
filing date -
Dec 17, 2004
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Abstract
The present invention provides cells having more than two drug resistance genes and at least two different resistance genes that have been recombined into the chromosome of a cell. It also teaches the processes for preparing cells by recombining two or more different drug resistance genes into the chromosome of a cell. The invention further shows a screening method using the cells of described herein that may be used to accomplish high throughput screening of, among other things, natural products and/or whole cells isolated from the environment.
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