Prodrugs and methods of making and using the same
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United States of America Patent
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N/A
Issued Date -
Dec 25, 2008
app pub date -
Dec 5, 2007
filing date -
Dec 5, 2006
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Prodrugs of parent drugs and methods of making and using the same are described. The prodrugs comprise an amine-containing parent drug moiety and a prodrug moiety, such as methoxyphosphonic acid or ethoxyphosphonic acid. The prodrugs may be employed in therapy for the treatment of various indications, such as pain, and in methods of decreasing the abuse potential of abuse-prone drugs and/or delaying the onset of parent drug activity and/or prolonging parent drug activity as compared to administration of a parent drug.
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