Treatment of implantable medical devices resistant to calcification
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United States of America Patent
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Issued Date -
Dec 25, 2008
app pub date -
Jun 18, 2008
filing date -
Jun 20, 2007
priority date (Note) -
Abandoned
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Abstract
Treatment of implantable medical devices resistant to calcification The invention relates to a method for treating an implant comprising a protein-based substrate, including the following steps in which: (A)--the protein-based substrate is treated with a compound containing at least one aldehyde group, then (B)--the substrate is treated with a compound comprising a borohydride, then (C)--the substrate resulting from step (B) is treated with a derivative containing a silane group. The invention also relates to the treated protein-based implant obtained at the end of this method.
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