Dek protein compositions and methods of using the same

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United States of America Patent

PATENT NO 8652467
APP PUB NO 20090004197A1
SERIAL NO

12090164

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Abstract

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The present invention relates to DEK protein compositions (e.g., antibodies, small molecule inhibitors, siRNAs) and methods of using the same. In particular, the present invention provides compositions and methods for treating autoimmune disease (e.g., juvenile rheumatoid arthritis, lupus, etc.) and for inhibiting inflammation (e.g., associated with autoimmune disease) and cellular chemotaxis (e.g., of neutrophils, NK cells and T cells). The present invention further provides a diagnostic marker (e.g., DEK antigen) for autoimmune disease.

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Patent Owner(s)

  • THE REGENTS OF THE UNIVERSITY OF MICHIGAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adams, Barbara S Ann Arbor, US 1 6
Khodadoust, Michael Ann Arbor, US 1 6
Markovitz, David M Ann Arbor, US 8 12
Mor-Vaknin, Nirit Ann Arbor, US 6 12

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