AGE-2 APTAMER

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20090023672A1
SERIAL NO

11814904

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

An AGE-2 aptamer which binds to a glyceraldehyde-derived advanced glycation end product (AGE-2) but not to human serum albumin and comprises at least 35 bases and in which the cytosine content in the bases is at least 35%, or the guanine content in the bases is at least 32%. Since the AGE-2 aptamer can be used for detecting AGE-2, it can be used as a reagent for detection/diagnosis, and an agent for prevention/treatment of AGE-2 involved diseases such as: diabetic complications such as diabetic retinopathy, diabetic nephropathy, and diabetic neuropathy; neurodegenerative diseases such as Alzheimer's disease; and proliferation, metastasis, and invasion of malignant tumors.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
KURUME UNIVERSITYKURUME-SHI FUKUOKA 830-0011

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Higashimoto, Yuichiro Fukuoka, JP 1 3
Inoue, Hiroyoshi Fukuoka, JP 22 90
Takeuchi, Masayoshi Toyama, JP 26 159
Yamagashi, Shoichi Fukuoka, JP 1 3

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation