Novel Phosphinic Acid-Containing Thyromimetics

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20090028925A1
SERIAL NO

11814819

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to compounds of phosphonic acid-containing T3 mimetics and monoesters thereof, stereoisomers, pharmaceutically acceptable salts, co-crystals, and prodrugs thereof and pharmaceutically acceptable salts and co-crystals of the prodrugs, as well as their preparation and uses for preventing and/or treating metabolic diseases such as obesity, NASH, hypercholesterolemia and hyperlipidemia, as well as associated conditions such as atherosclerosis, coronary heart disease, impaired glucose tolerance, metabolic syndrome x and diabetes.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
METABASIS THERAPEUTICS, INC.SAN DIEGO, CA47

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boyer, Serge H San Diego , US 15 181
Erion, Mark D Del Mar , US 63 1333
Jiang, Hongjian San Diego , US 9 36

Cited Art Landscape

Patent Info (Count) # Cites Year
 
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NOVARTIS AG (3)
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (5)
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Arthromics plc (1)
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* Cited By Examiner

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Patent Info (Count) # Cites Year
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (11)
* 2006/0205,669 G-type peptides and other agents to ameliorate atherosclerosis and other pathologies 13 2005
8048851 Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response 3 2007
7994132 Peptides for treatment of scleroderma 3 2007
7820784 Orally administered peptides synergize statin activity 5 2007
* 2008/0095,821 PEPTIDES AND PEPTIDE MIMETICS TO TREAT PATHOLOGIES CHARACTERIZED BY AN INFLAMMATORY RESPONSE 13 2007
* 2008/0096,816 ORALLY ADMINISTERED PEPTIDES SYNERGIZE STATIN ACTIVITY 14 2007
* 2008/0096,815 ORALLY ADMINISTERED PEPTIDES SYNERGIZE STATIN ACTIVITY 13 2007
* 2008/0293,639 PEPTIDES AND PEPTIDE MIMETICS TO TREAT PATHOLOGIES CHARACTERIZED BY AN INFLAMMATORY RESPONSE 13 2007
8236754 Methods for improving the structure and function of arterioles 2 2009
* 2010/0227,825 PEPTIDES AND PEPTIDE MIMETICS TO TREAT CANCER 7 2010
8404635 Orally administered peptides synergize statin activity 1 2011
 
GALECTIN THERAPEUTICS, INC. (3)
8658787 Galacto-rhamnogalacturonate compositions for the treatment of non-alcoholic steatohepatitis and non-alcoholic fatty liver disease 1 2012
9200090 Galactose-pronged polysaccharides in a formulation for antifibrotic therapies 1 2012
9763974 Galacto-rhamnogalacturonate compositions for the treatment of diseases associated with elevated inducible nitric oxide synthase 0 2013
 
LORD CORPORATION (2)
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* 2013/0309,508 ACRYLIC ADHESION PROMOTERS 0 2012
* Cited By Examiner