Novel Phosphinic Acid-Containing Thyromimetics

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United States of America Patent

APP PUB NO 20090028925A1
SERIAL NO

11814819

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Abstract

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The present invention relates to compounds of phosphonic acid-containing T3 mimetics and monoesters thereof, stereoisomers, pharmaceutically acceptable salts, co-crystals, and prodrugs thereof and pharmaceutically acceptable salts and co-crystals of the prodrugs, as well as their preparation and uses for preventing and/or treating metabolic diseases such as obesity, NASH, hypercholesterolemia and hyperlipidemia, as well as associated conditions such as atherosclerosis, coronary heart disease, impaired glucose tolerance, metabolic syndrome x and diabetes.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
METABASIS THERAPEUTICS, INC.SAN DIEGO, CA47

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boyer, Serge H San Diego , US 15 203
Erion, Mark D Del Mar , US 65 1467
Jiang, Hongjian San Diego , US 12 42

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