Novel Phosphinic Acid-Containing Thyromimetics
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United States of America Patent
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Issued Date -
Jan 29, 2009
app pub date -
May 26, 2006
filing date -
May 26, 2005
priority date (Note) -
Abandoned
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Abstract
The present invention relates to compounds of phosphonic acid-containing T3 mimetics and monoesters thereof, stereoisomers, pharmaceutically acceptable salts, co-crystals, and prodrugs thereof and pharmaceutically acceptable salts and co-crystals of the prodrugs, as well as their preparation and uses for preventing and/or treating metabolic diseases such as obesity, NASH, hypercholesterolemia and hyperlipidemia, as well as associated conditions such as atherosclerosis, coronary heart disease, impaired glucose tolerance, metabolic syndrome x and diabetes.
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