Process for Crystallizing Lactose Particles for Use in Pharmaceutical Formulations
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United States of America Patent
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Issued Date -
Jan 29, 2009
app pub date -
Jan 19, 2006
filing date -
Feb 10, 2005
priority date (Note) -
Abandoned
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Abstract
A process for producing a plurality of lactose particles comprises subjecting a plurality of lactose particles, to conditions such that at least a portion of smaller lactose particles detach from the plurality of the lactose particles and disperse in the liquid medium; subjecting the liquid medium to conditions sufficient to cause crystallization to occur on the smaller lactose particle surfaces to form larger lactose particles; and subjecting the liquid medium to conditions such that at least a portion of the lactose particles smaller relative to the plurality of larger lactose particles are dissolved in the liquid medium, wherein crystallization occurs on the plurality of larger lactose particles.
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