Methods of gene therapy using nucleic acid sequences for ATP-binding cassette transporter

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United States of America Patent

PATENT NO 8129353
APP PUB NO 20090029930A1
SERIAL NO

11636909

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Abstract

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The present invention provides nucleic acid and amino acid sequences of an ATP binding cassette transporter and mutated sequences thereof associated with macular degeneration. Methods of detecting agents that modify ATP-binding cassette transporter comprising combining purified ATP binding cassette transporter and at least one agent suspected of modifying the ATP binding cassette transporter an observing a change in at least one characteristic associated with ATP binding cassette transporter. Methods of detecting macular degeneration is also embodied by the present invention.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF UTAH RESEARCH FOUNDATION615 ARAPEEN DRIVE SUITE 310 SALT LAKE CITY UT 84108

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allikmets, Rando Frederick, US 25 212
Anderson, Kent L Houston, US 9 22
Dean, Michael Frederick, US 45 529
Leppert, Mark Salt Lake City, US 17 32
Lewis, Richard A Houston, US 35 710
Li, Yixin Houston, US 25 29
Lupski, James R Houston, US 17 240
Nathans, Jeremy Baltimore, US 18 48
Rattner, Amir Baltimore, US 6 16
Shroyer, Noah F Houston, US 10 59
Singh, Nanda Salt Lake City, US 6 16
Smallwood, Philip Woodbine, US 6 16
Sun, Hui Baltimore, US 131 907

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