Thermally Crosslinked Contrast Agents
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United States of America Patent
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Issued Date -
Feb 12, 2009
app pub date -
Aug 3, 2007
filing date -
Aug 3, 2007
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates to a contrast agent comprising a plurality of nanoparticles, wherein each of the nanoparticles comprises: (a) a signal generating core; and (b) a polymeric shell coated on the signal generating core, wherein the polymeric shell comprises a water soluble hydoxysilyl- or alkoxysilyl-functionalized polymer and wherein the polymer shell is thermally crosslinked through hydroxysilyl or alkoxysilyl groups of the polymer.
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