EXPRESSION OF SOLUBLE ANTIBODY FRAGMENT BY TRUNCATION OF CH1 DOMAIN
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United States of America Patent
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Issued Date -
Feb 12, 2009
app pub date -
Jun 6, 2008
filing date -
Jun 8, 2007
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Abandoned
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Abstract
1 region can be used as a scaffold to create other Fabs. Also included is truncation of the kappa light chain and/or lambda light chain domains of a Fab fragment. The invention also includes expression of Fab fragments fused to other peptides or molecules (e.g., toxins, proteins, peptides, enzymes, etc.).
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