RECOVERY OF VIRUS FROM CELL CULTURE USING HYPERTONIC SALT SOLUTION

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United States of America Patent

SERIAL NO

12209036

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Abstract

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A process of harvesting a herpesvirus from a cell culture infected therewith comprises treating said culture with a hypertonic aqueous salt solution to yield a virus suspension, e.g. to give improved yield of virus for live virus vaccine where otherwise cell-disruption might be used to harvest the virus by disrupting virus-infected cells. The harvesting step can be followed e.g. by nuclease treatment, diafiltration and lyophilisation.

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Patent OwnerAddress
XENOVA RESEARCH LIMITED184 CAMBRIDGE SCIENCE PARK MILTON ROAD CAMBRIDGE ENGLAND CB4 4GN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Johnston, Michael Denis Cambridge , GB 5 32
O'Keeffe, Roderic Simon Saffron Walden , GB 4 28

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