METHOD FOR EVALUATING DRUG CANDIDATES

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United States of America Patent

SERIAL NO

12202758

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Abstract

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Two-dimensional and/or three-dimensional polymeric or extended solid arrays, such as arrays of a polydiacetylene backbone, are used to evaluate the organic/water partition coefficient or oral absorptivity or transcellular permeability of a compound by monitoring the change in the fluorescence or phosphorescence of the array upon exposure to the compound and comparing it to a known change in fluorescence or phosphorescence, respectively. The method can also be used to evaluate the ability of a compound to bind to a protein.

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Patent Owner(s)

Patent OwnerAddress
ANALYTICAL BIOLOGICAL SERVICES INCWILMINGTON DE 19801

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Reppy, Mary A Wilmington, US 8 21
Saller, Charles F Escondido, US 7 15

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