CATALYTIC ANTIOXIDANTS AND METHODS OF USE
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United States of America Patent
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app pub date -
Aug 4, 2008
filing date -
Nov 26, 2002
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Abstract
The invention provides small molecules that act as catalytic antioxidants and methods of use thereof. The compounds can repeatedly bind and destroy reactive oxygen species by serving as substrates for enzymes of the methionine sulfoxide reductase (Msr) class. Some embodiments of the catalytic antioxidant compounds are derived from drugs with anti-inflammatory activity due to inhibition of cyclooxygenase enzymes.
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