SELF-ASSEMBLED PROTEINS AND RELATED METHODS

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United States of America Patent

APP PUB NO 20090093614A1
SERIAL NO

11751850

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Abstract

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The present invention provides user-directed construction of novel specific homo- and hetero-dimeric, and multimeric assemblages of proteins. The present invention is comprised of a family of peptide sequences that forms links between proteins, where the peptide sequences produce a hook or loop which supports specific self-assembly of dimers of the proteins to which they are attached. The hook or loop may have a short aliphatic repeat and a metal binding loop. Also provided is a method of constructing a hook motif of metal binding loop sequences attached to at least one aliphatic carbon sequence to produce homo-dimeric, hetero-dimeric and multimeric assemblages of proteins.

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Patent Owner(s)

Patent OwnerAddress
DUQUESNE UNIVERSITY OF THE HOLY GHOST600 FORBES AVENUE PITTSBURGH PA 15282

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dameron, Charles Pittsburgh, US 3 0

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