SYNTHESIS OF NOVEL TUBULIN POLYMERIZATION INHIBITORS: BENZOYLPHENYLUREA (BPU) SULFUR ANALOGS

United States of America Patent

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Issued Date
Apr 16, 2009
app pub date
Sep 16, 2008
filing date
Sep 17, 2007

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Abandoned

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Abstract

This invention provides a series of BPU analogues; their synthesis and evaluated biological activity. BPU sulfur analogues were found to possess up to 20 fold increased potency, when compared to compound 1, in various cancerous cell lines.

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Patent Owner	Address
CHAMPIONS BIOTECHNOLOGY INC	855 NORTH WOLFE STREET BALTIMORE MD 21205

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Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Hallur, Gurulingappa	Owlings Mills, US	16	40
Hidalgo, Manuel	Baltimore, US	69	323
Jimeno, Antonio	Englewood, US	11	40
Khan, Saeed R	Owlings Mills, US	9	39

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SYNTHESIS OF NOVEL TUBULIN POLYMERIZATION INHIBITORS: BENZOYLPHENYLUREA (BPU) SULFUR ANALOGS

Number of patents in Portfolio can not be more than 2000

United States of America Patent

12211492

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APP PUB NO	20090099218A1
SERIAL NO	12211492
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12211492

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