Multi-subunit biological complexes for treatment of plaque-associated diseases
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United States of America Patent
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Jan 13, 2015
Grant Date -
Apr 23, 2009
app pub date -
Sep 29, 2008
filing date -
Oct 5, 2007
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Abstract
Provided herein are methods and compositions for the in vitro formation of multi subunit biological platforms. The biological platforms may be used to screen chemical or biological compounds, in particular compounds that may disrupt or otherwise affect the formation of the multi subunit complexes, or disrupt already-formed in vitro assembled multi subunit complexes. Also provided herein are methods and compositions for the in vivo formation of multi-subunit biological complexes. The methods and compositions described herein may be used to develop animal models of diseases or disorders.
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