Importance

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Abstract

A method is disclosed to administer to a patient in need thereof a therapeutically effective amount of one or more therapeutic agents. The method provides a patient comprising a blood vessel, supplies a therapeutic agent comprising a plurality of gas-filled microspheres, and supplies a catheter comprising a proximal end, a distal end, and an infusion length disposed adjacent the distal end, where that infusion length is formed to include an infusion pattern comprising a plurality of apertures extending therethrough. The method catheterizes the blood vessel using the catheter, prepares an aqueous mixture comprising the first therapeutic agent, disposes that aqueous mixture in a container, interconnects the container to the proximal end of said catheter, and administers the aqueous mixture into the blood vessel through the plurality of apertures extending through the catheter.

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First Claim