Microarray having a chemical library of compounds

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20090124517A1
SERIAL NO

11985386

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A microarray and a process for making the microarray having a library of chemical compounds are disclosed herein. Each member of the library is attached at a known location. The microarray has a plurality of addressable electrodes and a porous reaction layer attached to each electrode. The porous reaction layer has reactive hydroxyl groups. Michael acceptors are attached to the porous reaction layer of selected electrodes. The Michael acceptors are attached at the hydroxyl groups using electrochemically-generated base that is generated by the selected electrodes and confined to the selected electrodes with the use of excess activated ester. At least one of a plurality of chemical compounds from a library of compounds is attached to the olefin of the plurality of Michael acceptors. Attachment occurs only at the selected electrodes having Michael acceptors with unreacted olefin. Each member of the library of compounds is attached to the known locations.

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Patent Owner(s)

Patent OwnerAddress
CUSTOMARRAY INC9911 WILLOWS ROAD NE SUITE 175 REDMOND WA 98052

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Maurer, Karl Mukilteo, US 31 262
Moeller, Kevin D Overland, US 5 20
Stuart, Melissae St. Louis, US 1 0

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