Methods of generating and screening for proteases with altered specificity
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United States of America Patent
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app pub date -
Dec 28, 2007
filing date -
Oct 2, 2002
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Abstract
Disclosed herein are methods for generating proteases with altered specificity for the target molecules they cleave. The invention further discloses methods of using these proteases to treat diseases in which the target proteins are involved with. Cleaving certain target proteins at certain substrate sequences with a protease is a method for treating these pathologies.
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