Methods For Separating Organelles
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United States of America Patent
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Issued Date -
Jun 4, 2009
app pub date -
Nov 30, 2007
filing date -
Nov 30, 2007
priority date (Note) -
Abandoned
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Abstract
Methods and kits for separating organelles of a specific type from a mixture of organelles of different types are described. The methods comprise providing a mixture of organelles of different types, adding probes to the mixture to form an organelle-probe complex with a distinct diffusion coefficient, and separating the organelles of the specific type from the mixture of organelles based upon the diffusion coefficient of the complex. The probes used in these methods include an affinity portion which binds selectively to the organelle of the specific type and a tag portion which imparts the distinct diffusion coefficient to the complex.
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