Preparation of templates for methylation analysis

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United States of America Patent

PATENT NO 9868982
SERIAL NO

12069174

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Abstract

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The invention relates to a method of preparing and using a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a method of preparing and analyzing a library of template polynucleotides suitable for methylation analysis.

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Patent Owner(s)

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MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gnirke, Andreas Cambridge, US 27 404
Gormley, Niall Essex, GB 12 33
Jaffe, David Cambridge, US 10 111
Nusbaum, Harris Cambridge, US 4 12

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