Protection of Photoreceptors in Experimental Autoimmune Uveitis
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United States of America Patent
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Issued Date -
Jun 11, 2009
app pub date -
Dec 9, 2008
filing date -
Dec 10, 2007
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Abandoned
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Abstract
Techniques are described for the administration of crystallins, e.g., αA and/or β crystallin, to protect retinal photoreceptors of subjects inoculated with Experimental Autoimmune Uveitis. The present disclosure provides a unique and novel approach to the prevention of photoreceptor degeneration in uveitis and other blinding diseases mediated by oxidative stress including retinitis pigmentosa, macular degeneration, diabetic retinopathy and glaucoma through the administration of crystalline, e.g., αA and/or β crystallin.
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