METHOD FOR ISOLATING STEM CELLS AND STEM CELLS DERIVED FROM A PAD-LIKE TISSUE OF TEETH
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United States of America Patent
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Issued Date -
Jun 25, 2009
app pub date -
Jul 17, 2006
filing date -
Jul 29, 2005
priority date (Note) -
Abandoned
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Abstract
The invention relates to a method for isolating non-embryonic stem cells from a tissue that is located in immediate vicinity of immature, developing teeth or wisdom teeth. The invention further relates to non-embryonic stem cells derived from said tissue. The method according to the invention utilises a living soft tissue residing underneath the dental papilla 12 in immediate vicinity of the apical side of a developing tooth, which is clearly distinguished from other tooth tissue, such as dental papilla 12 or follicle. The pad-like tissue 16 can only be detected in a defined, specific developmental stage in an early phase of root formation. That is, identifying and separating the pad-like tissue 16 is only possible from the appearance of the bony alveolar fundus to the end of the formation of the root of the tooth.
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