Medical implants with polysaccharide drug eluting coatings
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United States of America Patent
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May 10, 2011
Grant Date -
Aug 13, 2009
app pub date -
Feb 11, 2009
filing date -
Feb 12, 2008
priority date (Note) -
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Abstract
A medical implant can include a bioerodible metal portion and a coating overlying the bioerodible metal portion. The coating can include a therapeutic agent and a polysaccharide matrix reversibly cross-linked with polyvalent metal cations. Upon implantation of the implant within a body, the therapeutic agent is released and the bioerodible metal portion erodes to release polyvalent metal cations capable of re-cross-linking the polysaccharide matrix.
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