In vitro Assay Methods for Classifying Embryotoxicity of Compounds
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United States of America Patent
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Issued Date -
Sep 3, 2009
app pub date -
Mar 6, 2008
filing date -
Mar 6, 2007
priority date (Note) -
Abandoned
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Abstract
The present disclosure provides methods useful for screening compounds and/or compositions, for example potential drug candidates. The results of the screening assays correlate to the effects of the compounds on the molecular and/or cellular level of the human body. Also disclosed are screening assays utilizing human embryonic stem cells RELICELL®hES of Indian origin. The methods disclosed herein correlate well with animal preclinical toxicity studies done in a clinical trial setup.
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