Kallikrein Inhibitors and Anti-Thrombolytic Agents and Uses Thereof

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United States of America Patent

SERIAL NO

11932184

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Abstract

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Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass.

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Patent Owner(s)

Patent OwnerAddress
DYAX CORP300 SHIRE WAY LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beck, Thomas Concord , US 134 1614
Blair, Henry Boston , US 13 394
Ladner, Robert C Ijamsville , US 96 10156

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