Humanized antibodies that sequester amyloid beta peptide

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United States of America Patent

PATENT NO 7892545
SERIAL NO

12028641

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Abstract

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A method to treat conditions characterized by formation of amyloid plaques both prophylactically and therapeutically is described. The method employs humanized antibodies which sequester soluble Aβ peptide from human biological fluids or which preferably specifically bind an epitope contained within position 13-28 of the amyloid beta peptide Aβ.

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Patent Owner(s)

Patent OwnerAddress
WASHINGTON UNIVERSITYONE BROOKINGS DRIVE ST LOUIS MO 63130

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bales, Kelly R Indianapolis, US 9 278
DeMattos, Ronald Noblesville, US 7 274
Holtzman, David M St. Louis, US 11 302
Paul, Steven M Carmel, US 18 335
Tsurushita, Naoya Palo Alto, US 63 1794
Vasquez, Maximiliano Palo Alto, US 92 1921

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