Therapeutic Use of Methionine to Reduce the Toxicity of Aminoglycoside Antibiotics
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United States of America Patent
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app pub date -
Apr 6, 2009
filing date -
Oct 3, 1996
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Abstract
Methods of preventing or reducing ototoxicity in patients undergoing treatment with therapeutically effective amounts of aminoglycoside antibiotics are provided. The methods comprise administering an effective amount of an otoprotective agent comprising methionine or a methionine-like moiety to said patient prior to, simultaneously with, or subsequently to administration of the aminoglycoside antibiotic. Combinations of these time periods can also be employed.
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