SYSTEM FOR MONITORING BACTERIAL TUMOR TREATMENT
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United States of America Patent
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app pub date -
Apr 13, 2009
filing date -
Dec 31, 2001
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Abstract
A method to follow the progress of tumor treatment in subjects utilizes bacteria that have been modified to express a fluorescent protein. The method can also monitor expression of genes associated with the bacteria that produce therapeutic agents during the course of treatment, optionally against a background of fluorescence generated by the tumor itself. The method permits visualization of the progress of treatment in live subjects so that treatments can be modified according to their efficacy.
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