NUCLEAR TRANSPORT AGENT AND METHOD FOR PRODUCING SAID AGENT
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United States of America Patent
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Issued Date -
Oct 8, 2009
app pub date -
Sep 13, 2007
filing date -
Sep 13, 2006
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Abandoned
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Abstract
The present invention relates to a transport agent for transporting nucleic acids into eukaryotic cells and a method for producing said agent. The invention further concerns methods for transporting nucleic acids into eukaryotic cells using the transport agent according to the invention. The present invention provides an alternative transport agent and a method which are effective to allow an efficient transport of nucleic acids into eukaryotic cells. The transport agent comprises a complex forming moiety that is capable of forming complexes with at least one nucleic acid molecule and condensing said nucleic acid molecule, and at least one nuclear localization moiety comprising at least one nuclear localization signal and having an approximately neutral net charge.
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