Amyloid beta receptor and uses thereof
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United States of America Patent
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Issued Date -
Oct 15, 2009
app pub date -
Jul 27, 2006
filing date -
Jul 29, 2005
priority date (Note) -
Abandoned
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Abstract
The present invention relates to the identification that soluble assemblies of amyloid β function as a NMDA receptor antagonist. The present invention also provides methods and compositions for the detection and treatment of neurodegenerative and cognitive disorders and screening methods to identify agents that modulate the antagonistic effect of soluble assemblies of amyloid β on NMDA receptor function.
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