Methods and compositions for preventing bias in amplification and sequencing reactions
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United States of America Patent
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Issued Date -
Oct 22, 2009
app pub date -
Jan 23, 2009
filing date -
Jan 23, 2008
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Abstract
The present invention is directed to compositions and methods for nucleic acid identification and detection. Compositions and methods of the present invention include template nucleic acids with stabilizing sequences. The present invention also includes concatemers formed from template nucleic acids that have stabilizing sequences, arrays of such concatemers, as well as methods for identifying and detecting sequences of such concatemers.
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