Linear donor constructs for targeted integration
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United States of America Patent
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Issued Date -
Oct 22, 2009
app pub date -
Apr 13, 2009
filing date -
Apr 14, 2008
priority date (Note) -
Abandoned
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Abstract
Disclosed herein are linear donor molecules comprising homology arms of 50-750 base pairs (e.g., 50-100 base pairs) flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.
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