Solid pharmaceutical dosage forms comprising bisphosphonates and modified amino acid carriers

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9370492
APP PUB NO 20090281064A1
SERIAL NO

12504484

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention provides novel solid pharmaceutical dosage forms for oral administration comprising a bisphosphonate, or a pharmaceutically acceptable salt thereof, which bisphosphonate is present in an amount not therapeutically effective when the bisphosphonate is orally administered alone, and a modified amino acid carrier, or a pharmaceutically acceptable salt thereof, which modified amino acid carrier is present in an amount effective to facilitate absorption of the bisphosphonate in the gastrointestinal tract such that the bisphosphonate is therapeutically effective. The ratio of bisphosphonate to modified amino acid carrier is from about 1:30 to about 1:1, respectively. These novel solid pharmaceutical dosage forms are useful in the treatment or control of bone diseases and particular disorders in calcium metabolism, including, for example, osteoporosis, hypercalcaemia of cancer, and the treatment of metastatic bone pain. The present invention also provides a method for treating these diseases employing the solid pharmaceutical dosage forms and a method for preparing the pharmaceutical dosage forms.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
NOVO NORDISK NORTH AMERICA OPERATIONS A/SNOVO ALLÉ BAGSVAERD 2880

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahmed, Hashim Princeton, US 2 115
Bender, Lewis Redding, US 5 140
Infeld, Martin Howard Upper Montclair, US 13 144
Majuru, Shingai Brewster, US 47 387
Phuapradit, Wantanee Montville, US 78 571
Shah, Navnit Hargovindas Clifton, US 41 552
Yu, Zhongshui Williston Park, US 11 297

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
7.5 Year Payment $3600.00 $1800.00 $900.00 Dec 21, 2023
11.5 Year Payment $7400.00 $3700.00 $1850.00 Dec 21, 2027
Fee Large entity fee small entity fee micro entity fee
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00