Highly selective rho-kinase inhibitor

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United States of America Patent

APP PUB NO 20090306053A1
SERIAL NO

11919176

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a compound having a highly selective Rho-kinase inhibiting activity and being useful as a therapeutic agent for a disease such as hypertension, pulmonary hypertension, cerebral vasospasm, cardiac angina, cardiac failure, arteriosclerosis, glaucoma, dysuria, asthma, or erectile dysfunction, and a drug containing the compound.Provided is a homopiperazine derivative represented by General Formula (1), an acid addition salt thereof, or a solvate of the derivative or the salt:represents a hydrogen atom, a halogen atom, or a hydroxyl group).

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Patent Owner(s)

Patent OwnerAddress
D WESTERN THERAPEUTICS INSTITUTE INC1-18-11 NISHIKI NAKA-KU NAGOYA-SHI AICHI 4600003 ?4600003

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hidaka, Hiroyoshi Aichi , JP 27 369
Nakano, Hiroshi Ibaraki , JP 377 4094
Ozawa, Takatoshi Tokyo , JP 6 44
Sigyo, Hiromichi Tokyo , JP 2 13
Tamura, Masahiro Tokyo , JP 150 3467
Yamada, Hajima Tokyo , JP 1 3
Yoshizaki, Hideo Shaitama , JP 24 159

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