RIBOZYME MEDIATED STABILIZATION OF POLYNUCLEOTIDES
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United States of America Patent
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Issued Date -
Dec 10, 2009
app pub date -
Jun 19, 2007
filing date -
Jun 19, 2006
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates to the production of novel, recombinant polynucleotides comprising the GIR1 ribozyme, or a variant thereof, vectors comprising such polynucleotides and recombinant host cells comprising such polynucleotides and/or such vectors. The invention furthermore relates to the use of said polynucleotides in the treatment of an individual suffering from a disease associated with or caused by instability of a transcript of said second subsequence such as cancer, cachexia, α-Thallasemia or leukaemia.
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International Classification(s)
- C07H:SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTI....
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- A01K:ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; ....
- A01H:NEW PLANTS OR PROCESSES FOR OBTAINING THEM; PLANT ....
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