Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20090319045A1
SERIAL NO

12381072

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Constructs that are at least partially constructed of allograft cancellous bone are disclosed, along with cartilage particles that may be used with the constructs for repairing articular cartilage defects. A multi-piece construct includes a base member, a cap member and at least one pin that secures the cap member to the base member. The base member may be constructed of mineralized cancellous bone, and is used to replace the subchondral bone removed when a surgeon cuts a bore in the area of an adjacent cartilage defect. The base member includes a blind bore and first and second through-going transverse bores in opposite sides of a wall of the base member. The cap member includes an upper section that has a thickness that is similar to that of a patient's surrounding articular cartilage layer and a stem depending from the upper section that is dimensioned to be received in and by the blind bore of the base member. The stem includes a transverse through-going bore, which may be aligned with the transverse through-going bores of the base member to receive the pin therein when the construct has been assembled. The cap member is at least partially formed of demineralized allograft cancellous bone, into which a mixture containing lyophilized, freeze-milled allograft cartilage particles may be infused for the repair of articular cartilage defects. The cartilage particles have a size within a range of from about 10 microns to about 210 microns.

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Patent Owner(s)

Patent OwnerAddress
MUSCULOSKELETAL TRANSPLANT FOUNDATION125 MAY STREET SUITE 300 EDISON NJ 08837

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Callahan, Alex B Perth Amboy , US 7 235
Gertzman, Arthur A Flemington , US 69 5837
Huang, Yen-Chen East Brunswick , US 30 516
Jacobs, Morris L Newtown , US 4 160
Munson, John C Easton , US 11 540
Semler, Eric J Piscataway , US 18 471
Shikhanovich, Roman Edison , US 11 235
Sunwoo, Moon Hae Old Tappan , US 46 2671
Tomford, William W Belmont , US 14 641
Truncale, Katherine G Hillsborough , US 14 483
Yannariello-Brown, Judith I Somerset , US 11 530

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