Mass spectrometric detection of material transferred to a surface
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United States of America Patent
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Aug 16, 2011
Grant Date -
Dec 31, 2009
app pub date -
Jun 2, 2009
filing date -
Jun 2, 2008
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Abstract
The present invention provides methods for using detection methods, including mass spectrometry methods such as SELDI-TOF-MS, to detect and analyze molecules directly transferred from a sample to a surface to form a molecular print of the sample. Methods and compositions of the invention can be used to produce spatially and non-spatially oriented molecular prints for detection using methods such as mass spectrometry. Methods and compositions of the invention encompass molecular printing of tissues, cells and gels onto surfaces.
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