Extended release pharmaceutical formulation of metoprolol and process for its preparation
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United States of America Patent
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N/A
Issued Date -
Dec 31, 2009
app pub date -
Jul 26, 2007
filing date -
Jul 28, 2006
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The invention provides an extended release coated granule comprising a granule having a particle size ranging from 0.2 to 2 mm, a friability lower than or equal to 1% and comprising metoprolol succinate as active ingredient in an amount ranging from 10 to 75% by weight of the granule and at least one binder selected from microcrystalline cellulose and methylcellulose, coated with a film-former coating agent. It also provides a process for the preparation of said extended release coated granules, as well as pharmaceutical formulations containing them.
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