Bone Defect Filler, Release-Controlled Carrier, And Their Production Methods
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United States of America Patent
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N/A
Issued Date -
Jan 7, 2010
app pub date -
Nov 8, 2007
filing date -
Nov 11, 2006
priority date (Note) -
Abandoned
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Abstract
A bone filling material having controlled release of a pharmaceutical agent such as a growth factor, and a drug release controlling carrier having controlled release of a pharmaceutical agent is provided by inactivating a functional group which can strongly bind to the pharmaceutical agent of the bone filling material with a blocking agent. The bone filling material and the drug release controlling carrier of the present invention comprises: a calcium-based material such as hydroxyapatite, carbonate apatite, fluorapatite, chlorapatite, β-TCP, and α-TCP; a blocking agent of the calcium-based material such as serine and dextran; and a pharmaceutical agent.
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