Drug-Eluting Endoprosthesis
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United States of America Patent
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Issued Date -
Jan 14, 2010
app pub date -
Dec 12, 2008
filing date -
Dec 14, 2007
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A drug-eluting endoprosthesis that includes a bioerodible metal portion and a therapeutic agent. In some aspects, the endoprosthesis includes a plurality of discrete deposits and a plurality of overlying layers each overlying one of the plurality of discrete deposits. Each discrete deposit includes one or more therapeutic agents and each overlying layer includes one or more bioerodible metals. In other aspects, the bioerodible metal portion includes at least two bioerodible metal regions having different electronegativities. The at least two bioerodible metal regions being in electrical contact with each other. The bioerodible metal erodes in a physiological environment to release the therapeutic agent.
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