NOVEL MULTIVALENT IMMUNOGLOBULINS
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United States of America Patent
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app pub date -
Jun 26, 2007
filing date -
Jul 5, 2006
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Abstract
The present invention provides a multivalent immunoglobulin or part thereof binding specifically to at least two cell surface molecules of a single cell with at least one modification in at least one structural loop region of said immunoglobulin determining binding to an epitope of said cell surface molecules wherein the unmodified immunoglobulin does not significantly bind to said epitope, its use and methods for producing it.
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