INDOLEAMINE 2,3-DIOXYGENASE, PD-1/PD-L PATHWAYS, AND CTLA4 PATHWAYS IN THE ACTIVATION OF REGULATORY T CELLS

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United States of America Patent

APP PUB NO 20100055111A1
SERIAL NO

12526909

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention includes methods of enhancing immune responses by administering an inhibitor of indoleamine-2,3-dioxygenase (IDO) along with one or more inhibitors of the PD-1/PD-L pathway and/or one or more inhibitors of the CTLA4 pathway.

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Patent Owner(s)

Patent OwnerAddress
MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE INC1120 15TH STREET CJ-3301 AUGUSTA GA 30912

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blazar, Bruce R Golden Valley, US 37 148
Mellor, Andrew L Augusta, US 11 88
Munn, David H Augusta, US 13 89
Sharma, Madhav D Augusta, US 2 27

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