PH Tolerant Luciferase

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United States of America Patent

APP PUB NO 20100068739A1
SERIAL NO

11990228

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Abstract

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(SEQ ID NO:1) in a method that is performed at a pH below the optimal pH for the wild-type luciferase during at least part of the time period over which bioluminescence measurements are taken, wherein the specific activity of the mutant luciferase is higher than the specific activity of wild-type at the pH at which the method is carried out.

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Patent Owner(s)

Patent OwnerAddress
CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED16 MILL LANE CB2 12B CAMBRIDGE
LUMORA LIMITEDCAMBRIDGE CB21 5XE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gandelman, Olga Cambridge, GB 4 10
Law, Gim Hoong Erica Cambridge, GB 1 0
Murray, James Augustus Henry Cambridge, GB 6 58
Tisi, Laurence Cambridge, GB 1 0

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